Effects of Increased Renal Tubular Vascular Endothelial Growth Factor (VEGF) on Fibrosis, Cyst Formation, and Glomerular Disease

The role of vascular endothelial growth factor (VEGF) in renal fibrosis, tubular cyst formation, and glomerular diseases is incompletely understood. We studied a new conditional transgenic mouse system [Pax8-rtTA/(tetO)(7)VEGF], which allows increased tubular VEGF production in adult mice. The follo...

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Detalhes bibliográficos
Main Authors: Hakroush, Samy, Moeller, Marcus J., Theilig, Franziska, Kaissling, Brigitte, Sijmonsma, Tjeerd P., Jugold, Manfred, Akeson, Ann L., Traykova-Brauch, Milena, Hosser, Hiltraud, Hähnel, Brunhilde, Gröne, Hermann-Josef, Koesters, Robert, Kriz, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774053/
https://ncbi.nlm.nih.gov/pubmed/19834063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080792
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