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Oxidation of multiple methionine residues impairs rapid sodium channel inactivation

Reactive oxygen species (ROS) readily oxidize the sulfur-containing amino acids cysteine and methionine (Met). The impact of Met oxidation on the fast inactivation of the skeletal muscle sodium channel Na(V)1.4 expressed in human embryonic kidney cells was studied by applying the Met-preferring oxid...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kassmann, Mario, Hansel, Alfred, Leipold, Enrico, Birkenbeil, Jan, Lu, Song-Qing, Hoshi, Toshinori, Heinemann, Stefan H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913308/
https://ncbi.nlm.nih.gov/pubmed/18369661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0477-6
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