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Oxidation of multiple methionine residues impairs rapid sodium channel inactivation
Reactive oxygen species (ROS) readily oxidize the sulfur-containing amino acids cysteine and methionine (Met). The impact of Met oxidation on the fast inactivation of the skeletal muscle sodium channel Na(V)1.4 expressed in human embryonic kidney cells was studied by applying the Met-preferring oxid...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913308/ https://ncbi.nlm.nih.gov/pubmed/18369661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-008-0477-6 |
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