Yüklüyor......
Three methionine residues located within the regulator of conductance for K(+) (RCK) domains confer oxidative sensitivity to large-conductance Ca(2)(+)-activated K(+) channels
Methionine-directed oxidation of the human Slo1 potassium channel (hSlo1) shifts the half-activation voltage by −30 mV and markedly slows channel deactivation at low concentrations of intracellular Ca(2)(+) ([Ca(2)(+)](i)). We demonstrate here that the contemporaneous mutation of M536, M712 and M739...
Kaydedildi:
| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2006
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796801/ https://ncbi.nlm.nih.gov/pubmed/16396928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.101089 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|