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Large-conductance Ca(2+)- and voltage-gated K(+) channels form and break interactions with membrane lipids during each gating cycle
Membrane depolarization and intracellular Ca(2+) promote activation of the large-conductance Ca(2+)- and voltage-gated (Slo1) big potassium (BK) channel. We examined the physical interactions that stabilize the closed and open conformations of the ion conduction gate of the human Slo1 channel using...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486743/ https://ncbi.nlm.nih.gov/pubmed/30967508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901381116 |
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