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Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry
Dynamic covalent chemistry uses reversible chemical reactions to set up an equilibrating network of molecules at thermodynamic equilibrium, which can adjust its composition in response to any agent capable of altering the free energy of the system. When the target is a biological macromolecule, such...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913121/ https://ncbi.nlm.nih.gov/pubmed/20489719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.658 |
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