Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (−) cells (mutations Chartres 1 and 2)

BACKGROUND: Protein 4.2 deficiency caused by mutations in the EPB42 gene results in hereditary spherocytosis with characteristic alterations of CD47, CD44 and RhAG. We decided to investigate at which stage of erythropoiesis these hallmarks of protein 4.2 deficiency arise in a novel protein 4.2 patie...

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Hlavní autoři: van den Akker, Emile, Satchwell, Timothy J., Pellegrin, Stephanie, Flatt, Joanna F., Maigre, Michel, Daniels, Geoff, Delaunay, Jean, Bruce, Lesley J., Toye, Ashley M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913075/
https://ncbi.nlm.nih.gov/pubmed/20179084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.021063
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