The majority of the in vitro erythroid expansion potential resides in CD34(−) cells, outweighing the contribution of CD34(+) cells and significantly increasing the erythroblast yield from peripheral blood samples

The study of human erythropoiesis in health and disease requires a robust culture system that consistently and reliably generates large numbers of immature erythroblasts that can be induced to differentiate synchronously. We describe a culture method modified from Leberbauer et al. (2005) and obtain...

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Bibliographic Details
Main Authors: van den Akker, Emile, Satchwell, Timothy J., Pellegrin, Stephanie, Daniels, Geoff, Toye, Ashley M.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2010
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930963/
https://ncbi.nlm.nih.gov/pubmed/20378567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.019828
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