Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal

The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34(+) cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 2...

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Detalhes bibliográficos
Main Authors: Pellegrin, Stéphanie, Heesom, Kate J., Satchwell, Timothy J., Hawley, Bethan R., Daniels, Geoff, van den Akker, Emile, Toye, Ashley M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377639/
https://ncbi.nlm.nih.gov/pubmed/22723854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038356
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