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Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model
BACKGROUND: Mutations in the gene encoding the E3 ubiquitin ligase parkin (PARK2) are responsible for the majority of autosomal recessive parkinsonism. Similarly to other knockout mouse models of PD-associated genes, parkin knockout mice do not show a substantial neuropathological or behavioral phen...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912770/ https://ncbi.nlm.nih.gov/pubmed/20689587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011783 |
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