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Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

Oncogene-mediated transformation of hematopoietic cells has been studied extensively, but little is known about the molecular basis for restriction of oncogenes to certain target cells and differential cellular context-specific requirements for oncogenic transformation between infant and adult leuke...

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Autori principali: Klusmann, Jan-Henning, Godinho, Frank J., Heitmann, Kirsten, Maroz, Aliaksandra, Lee Koch, Mia, Reinhardt, Dirk, Orkin, Stuart H., Li, Zhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912563/
https://ncbi.nlm.nih.gov/pubmed/20679399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1903410
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