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RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage
Dnmt2 proteins are the most conserved members of the DNA methyltransferase enzyme family, but their substrate specificity and biological functions have been a subject of controversy. We show here that, in addition to tRNA(Asp-GTC), tRNA(Val-AAC) and tRNA(Gly-GCC) are also methylated by Dnmt2. Drosop...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912555/ https://ncbi.nlm.nih.gov/pubmed/20679393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.586710 |
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