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Functional and Structural Analysis of a Key Region of the Cell Wall Inhibitor Moenomycin
Moenomycin A (MmA) belongs to a family of natural products that inhibit peptidoglycan biosynthesis by binding to the peptidoglycan glycosyltransferases (PGTs), the enzymes that make the glycan chains of peptidoglycan. MmA is remarkably potent, but its clinical utility has been hampered by poor physi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912422/ https://ncbi.nlm.nih.gov/pubmed/20496948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100048q |
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