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Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis

Peptidoglycan is an essential polymer that forms a protective shell around bacterial cell membranes. Peptidoglycan biosynthesis is the target of many clinically used antibiotics, including the β-lactams, imipenems, cephalosporins, and glycopeptides. Resistance to these and other antibiotics has prom...

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Détails bibliographiques
Auteurs principaux: Yuan, Yanqiu, Barrett, Dianah, Zhang, Yi, Kahne, Daniel, Sliz, Piotr, Walker, Suzanne
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817829/
https://ncbi.nlm.nih.gov/pubmed/17360321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701160104
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