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The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases

The peptidoglycan glycosyltransferases (PGTs) catalyze the processive polymerization of a C55 lipid-linked disaccharide (Lipid II) to form peptidoglycan, the main component of the bacterial cell wall. Our ability to understand this reaction has been limited due to challenges identifying the appropri...

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Detalhes bibliográficos
Main Authors: Perlstein, Deborah L., Wang, Tsung-Shing Andrew, Doud, Emma H., Kahne, Daniel, Walker, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830065/
https://ncbi.nlm.nih.gov/pubmed/20017480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909325m
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