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Recognition of Platinum-DNA Damage by Poly(ADP-Ribose) Polymerase-1
Poly(ADP-ribose) polymerase-1 (PARP-1) was recently identified as a platinum DNA damage response protein. To investigate the binding properties of PARP-1 to different platinum-DNA adducts in greater detail, biotinylated DNA probes containing a site-specific cisplatin 1,2-d(GpG) or 1,3-d(GpTpG) intra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912421/ https://ncbi.nlm.nih.gov/pubmed/20550106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100775t |
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