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Poly(ADP-ribose) Polymerase-1 Activity Facilitates the Dissociation of Nuclear Proteins from Platinum-Modified DNA
The affinity of the poly(ADP-ribose) polymerase-1 (PARP-1) for platinum-damaged DNA was first discovered during photo-crosscroxss-linking experiments using the photoactive compound Pt-BP6 (Zhang, C. X.; Chang, P. V.; Lippard, S. J., J. Am. Chem. Soc. 2004, 126, 6536–6537), an analogue of the antican...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662712/ https://ncbi.nlm.nih.gov/pubmed/18977144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.09.074 |
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