Butyrylcholinesterase and G116H, G116S, G117H, G117N, E197Q and G117H/E197Q Mutants: A Molecular Dynamics Study

Butyrylcholinesterase (BuChE) is a stoichiometric bioscavenger against organophosphorus (OP) nerve agent poisoning, and efforts to make BuChE variants that are catalytically active against a wide spectrum of nerve agents have been ongoing for the last decade. In order to understand the structural co...

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Detaylı Bibliyografya
Asıl Yazarlar: Vyas, Shubham, Beck, Jeremy M., Xia, Shijing, Zhang, Jun, Hadad, Christopher M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912153/
https://ncbi.nlm.nih.gov/pubmed/20399202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.04.004
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