Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

Aberrant cell cycle activity and DNA damage are emerging as important pathological components in various neurodegenerative conditions. However, their underlying mechanisms are poorly understood. Here, we show that deregulation of HDAC1 activity by p25/Cdk5 induces aberrant cell cycle activity and do...

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書誌詳細
主要な著者: Kim, Dohoon, Frank, Christopher L., Dobbin, Matthew M., Tsunemoto, Rachel K., Wu, Di, Peng, Peter L., Guan, Ji-Song, Lee, Byung-Hoon, Moy, Lily Y., Giusti, Paola, Broodie, Nisha, Mazitschek, Ralph, Delalle, Ivanna, Haggarty, Stephen J., Neve, Rachael L., Lu, YouMing, Tsai, Li-Huei
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912147/
https://ncbi.nlm.nih.gov/pubmed/19081376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.10.015
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