Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

Aberrant cell cycle activity and DNA damage are emerging as important pathological components in various neurodegenerative conditions. However, their underlying mechanisms are poorly understood. Here, we show that deregulation of HDAC1 activity by p25/Cdk5 induces aberrant cell cycle activity and do...

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Detalhes bibliográficos
Main Authors: Kim, Dohoon, Frank, Christopher L., Dobbin, Matthew M., Tsunemoto, Rachel K., Wu, Di, Peng, Peter L., Guan, Ji-Song, Lee, Byung-Hoon, Moy, Lily Y., Giusti, Paola, Broodie, Nisha, Mazitschek, Ralph, Delalle, Ivanna, Haggarty, Stephen J., Neve, Rachael L., Lu, YouMing, Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912147/
https://ncbi.nlm.nih.gov/pubmed/19081376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.10.015
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