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The folding cooperativity of a protein is controlled by its chain topology
The three-dimensional structures of proteins often show a modular architecture comprised of discrete structural regions or domains. Cooperative communication between these regions is important for catalysis, regulation and efficient folding; lack of coupling has been implicated in the formation of f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911970/ https://ncbi.nlm.nih.gov/pubmed/20495548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09021 |
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