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Theory for protein folding cooperativity: helix-bundles

We present a theory for protein folding stability and cooperativity for helix bundle proteins. We treat the individual helices with a Schellman-Zimm-Bragg-like approach, using nucleation and propagation quantities, and we treat the hydrophobic and van der Waals contacts between the helices as a bind...

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Detalhes bibliográficos
Main Authors: Ghosh, Kingshuk, Dill, K. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654554/
https://ncbi.nlm.nih.gov/pubmed/19170581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808136x
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