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Differences in the Large Extracellular Loop between the K(+)-Cl(−) Cotransporters KCC2 and KCC4
K(+)Cl(−) cotransporters (KCCs) play fundamental physiological roles in processes such as inhibitory neurotransmission and cell volume regulation. Mammalian genomes encode four distinct KCC paralogs, which share basic transport characteristics but differ significantly in ion affinity, pharmacology,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911324/ https://ncbi.nlm.nih.gov/pubmed/20516068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144063 |
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