Starvation-induced Hyperacetylation of Tubulin Is Required for the Stimulation of Autophagy by Nutrient Deprivation

The molecular mechanisms underlying microtubule participation in autophagy are not known. In this study, we show that starvation-induced autophagosome formation requires the most dynamic microtubule subset. Upon nutrient deprivation, labile microtubules specifically recruit markers of autophagosome...

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Detalhes bibliográficos
Main Authors: Geeraert, Camille, Ratier, Ameetha, Pfisterer, Simon G., Perdiz, Daniel, Cantaloube, Isabelle, Rouault, Audrey, Pattingre, Sophie, Proikas-Cezanne, Tassula, Codogno, Patrice, Poüs, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911293/
https://ncbi.nlm.nih.gov/pubmed/20484055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091553
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