Reactive Oxygen Species, AMP-activated Protein Kinase, and the Transcription Cofactor p300 Regulate α-Tubulin Acetyltransferase-1 (αTAT-1/MEC-17)-dependent Microtubule Hyperacetylation during Cell Stress

Beyond its presence in stable microtubules, tubulin acetylation can be boosted after UV exposure or after nutrient deprivation, but the mechanisms of microtubule hyperacetylation are still unknown. In this study, we show that this hyperacetylation is a common response to several cellular stresses th...

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Detaylı Bibliyografya
Asıl Yazarlar: Mackeh, Rafah, Lorin, Séverine, Ratier, Ameetha, Mejdoubi-Charef, Najet, Baillet, Anita, Bruneel, Arnaud, Hamaï, Ahmed, Codogno, Patrice, Poüs, Christian, Perdiz, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002089/
https://ncbi.nlm.nih.gov/pubmed/24619423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507400
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