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Design and evaluation of genome-wide libraries for RNA interference screens

RNA interference (RNAi) screens have enabled the systematic analysis of many biological processes in cultured cells and whole organisms. The success of such screens and the interpretation of the data depend on the stringent design of RNAi libraries. We describe and validate NEXT-RNAi, a software for...

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Detalhes bibliográficos
Main Authors: Horn, Thomas, Sandmann, Thomas, Boutros, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911109/
https://ncbi.nlm.nih.gov/pubmed/20550664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-6-r61
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