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Inflammasome inhibition as a pathogenic stealth mechanism

The activation of inflammasomes containing NBD-LRR (NLRs) or non-NLRs is critical for effective host defense against microbial pathogens. Recent discoveries have uncovered a plethora of pathogenic strategies to inhibit inflammasome-mediated processing of IL-1β and IL-18. We review recent evidence fo...

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Bibliografiske detaljer
Main Authors: Taxman, Debra J., Huang, Max T.-H., Ting, Jenny P.-Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911019/
https://ncbi.nlm.nih.gov/pubmed/20638636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.06.005
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