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Inflammasome inhibition as a pathogenic stealth mechanism

The activation of inflammasomes containing NBD-LRR (NLRs) or non-NLRs is critical for effective host defense against microbial pathogens. Recent discoveries have uncovered a plethora of pathogenic strategies to inhibit inflammasome-mediated processing of IL-1β and IL-18. We review recent evidence fo...

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Bibliografische gegevens
Hoofdauteurs: Taxman, Debra J., Huang, Max T.-H., Ting, Jenny P.-Y.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911019/
https://ncbi.nlm.nih.gov/pubmed/20638636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.06.005
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