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POLY(ADP-RIBOSE) POLYMERASE-1 IS A DETERMINING FACTOR IN CRM1-MEDIATED NUCLEAR EXPORT AND RETENTION OF P65 NF-κB UPON TLR4 STIMULATION
The role of NF-κB in the expression of inflammatory genes and its participation in the overall inflammatory process of chronic diseases and acute tissue injury are well-established. We and others have demonstrated a critical involvement of poly(ADP-ribose) polymerase (PARP)-1 during inflammation, in...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910824/ https://ncbi.nlm.nih.gov/pubmed/20610652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000646 |
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