Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

BACKGROUND: Mutation analysis of KIT and PDGFRA genes in gastrointestinal stromal tumors is gaining increasing importance for prognosis of GISTs and for prediction of treatment response. Several groups have identified specific mutational subtypes in KIT exon 11 associated with an increased risk of m...

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Detaylı Bibliyografya
Asıl Yazarlar: Merkelbach-Bruse, Sabine, Dietmaier, Wolfgang, Füzesi, Laszlo, Gaumann, Andreas, Haller, Florian, Kitz, Julia, Krohn, Antje, Mechtersheimer, Gunhild, Penzel, Roland, Schildhaus, Hans-Ulrich, Schneider-Stock, Regine, Simon, Ronald, Wardelmann, Eva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Technical Advance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910708/
https://ncbi.nlm.nih.gov/pubmed/20598160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-106
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