Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

Eitemau Tebyg

• The location of KIT and PDGFRA gene mutations in gastrointestinal stromal tumours is site and phenotype associated
  gan: Penzel, R, et al.
  Cyhoeddwyd: (2005)
• Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors
  gan: Gao, Jing, et al.
  Cyhoeddwyd: (2016)
• Utility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissue
  gan: FASSUNKE, JANA, et al.
  Cyhoeddwyd: (2015)
• A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)
  gan: Huss, Sebastian, et al.
  Cyhoeddwyd: (2013)
• c-KIT and PDGFRA in breast phyllodes tumours: overexpression without mutations?
  gan: Carvalho, S, et al.
  Cyhoeddwyd: (2004)