Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

BACKGROUND: Mutation analysis of KIT and PDGFRA genes in gastrointestinal stromal tumors is gaining increasing importance for prognosis of GISTs and for prediction of treatment response. Several groups have identified specific mutational subtypes in KIT exon 11 associated with an increased risk of m...

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Bibliografiska uppgifter
Huvudupphovsmän: Merkelbach-Bruse, Sabine, Dietmaier, Wolfgang, Füzesi, Laszlo, Gaumann, Andreas, Haller, Florian, Kitz, Julia, Krohn, Antje, Mechtersheimer, Gunhild, Penzel, Roland, Schildhaus, Hans-Ulrich, Schneider-Stock, Regine, Simon, Ronald, Wardelmann, Eva
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Technical Advance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910708/
https://ncbi.nlm.nih.gov/pubmed/20598160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-106
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