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Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Loss of dystrophin results in disruption of a large dystrophin glycoprotein complex (DGC) leading to pathologic calcium (Ca(2+))-dependent signals that damage muscl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910579/ https://ncbi.nlm.nih.gov/pubmed/19198614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1916 |
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