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Ryanodine receptor/calcium release channel PKA phosphorylation: A critical mediator of heart failure progression

Defective regulation of the cardiac ryanodine receptor (RyR2)/calcium release channel, required for excitation-contraction coupling in the heart, has been linked to cardiac arrhythmias and heart failure. For example, diastolic calcium “leak” via RyR2 channels in the sarcoplasmic reticulum has been i...

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Bibliografiset tiedot
Päätekijät: Wehrens, Xander H. T., Lehnart, Stephan E., Reiken, Steven, Vest, John A., Wronska, Anetta, Marks, Andrew R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334677/
https://ncbi.nlm.nih.gov/pubmed/16407108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510113103
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