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Increased expression of HIF-1α, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency

PURPOSE: A mouse model of renal insufficiency with arteriovenous fistula (AVF) and venous stenosis was created. We tested the hypothesis that there is increased gene expression of hypoxia inducible factor-1 alpha (HIF-1α), vascular endothelial growth factor- A (VEGF-A) and its receptors (VEGFR-1, -2...

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Main Authors: Misra, Sanjay, Shergill, Uday, Yang, Binxia, Janardhanan, Rajiv, Misra, Khamal D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910198/
https://ncbi.nlm.nih.gov/pubmed/20598569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvir.2010.02.043
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