Adventitial Delivery of Lentivirus-shRNA-ADAMTS-1 Reduces Venous Stenosis Formation in Arteriovenous Fistula

Hemodialysis vascular access can develop venous neointimal hyperplasia (VNH) causing stenosis. Recent clinical and experimental data has demonstrated that there is increased expression of a disintegrin and metalloproteinase thrombospondin motifs-1 (ADAMTS-1) at site of VNH. The experiments outlined...

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Detalhes bibliográficos
Main Authors: Nieves Torres, Evelyn C., Yang, Binxia, Janardhanan, Rajiv, Brahmbhatt, Akshaar, Leof, Ed, Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986087/
https://ncbi.nlm.nih.gov/pubmed/24732590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094510
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