Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation

Venous neointimal hyperplasia (VNH) causes hemodialysis vascular access failure. Here we tested whether VNH formation occurs in part due to local vessel hypoxia caused by surgical trauma to the vasa vasorum of the outflow vein at the time of arteriovenous fistula placement. Selective targeting of th...

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Detalhes bibliográficos
Main Authors: Yang, Binxia, Janardhanan, Rajiv, Vohra, Pawan, Greene, Eddie L, Bhattacharya, Santanu, Withers, Sarah, Roy, Bhaskar, Nieves Torres, Evelyn C, Mandrekar, Jaywant, Leof, Edward B, Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844094/
https://ncbi.nlm.nih.gov/pubmed/23924957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.290
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