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Conformational Characterization of Aberrant Disulfide-linked HIV-1 gp120 Dimers Secreted from Overexpressing Cells

The envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) mediate viral entry and are also the primary target of neutralizing antibodies. The gp160 envelope glycoprotein precursor undergoes proteolytic cleavage in the Golgi complex to produce the gp120 exterior glycoprotein and the gp...

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Autors principals: Finzi, Andrés, Pacheco, Beatriz, Zeng, Xin, Do Kwon, Young, Kwong, Peter D., Sodroski, Joseph
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910153/
https://ncbi.nlm.nih.gov/pubmed/20471426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2010.05.008
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