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Optimal design of parallel triplex forming oligonucleotides containing Twisted Intercalating Nucleic Acids—TINA
Twisted intercalating nucleic acid (TINA) is a novel intercalator and stabilizer of Hoogsteen type parallel triplex formations (PT). Specific design rules for position of TINA in triplex forming oligonucleotides (TFOs) have not previously been presented. We describe a complete collection of easy and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910062/ https://ncbi.nlm.nih.gov/pubmed/20338879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq188 |
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