Visualizing helicases unwinding DNA at the single molecule level

DNA helicases are motor proteins that catalyze the unwinding of double-stranded DNA into single-stranded DNA using the free energy from ATP hydrolysis. Single molecule approaches enable us to address detailed mechanistic questions about how such enzymes move processively along DNA. Here, an optical...

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Main Authors: Fili, Natali, Mashanov, Gregory I., Toseland, Christopher P., Batters, Christopher, Wallace, Mark I., Yeeles, Joseph T. P., Dillingham, Mark S., Webb, Martin R., Molloy, Justin E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910053/
https://ncbi.nlm.nih.gov/pubmed/20350930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq173
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