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Potent and Selective Inhibition of the Open-Channel Conformation of AMPA Receptors by an RNA Aptamer
Inhibitors of AMPA receptors are useful as biochemical probes for structure-function studies and as drug candidates for a number of neurological disorders and diseases. Here we report the identification of an RNA inhibitor or aptamer by an in vitro evolution approach. Using a laser-pulse photolysis...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908592/ https://ncbi.nlm.nih.gov/pubmed/20518485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100690k |
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