Tumor Associated Macrophages Protect Colon Cancer Cells from TRAIL-Induced Apoptosis through IL-1β- Dependent Stabilization of Snail in Tumor Cells

BACKGROUND: We recently reported that colon tumor cells stimulate macrophages to release IL-1β, which in turn inactivates GSK3β and enhances Wnt signaling in colon cancer cells, generating a self-amplifying loop that promotes the growth of tumor cells. PRINCIPAL FINDINGS: Here we describe that macro...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaler, Pawan, Galea, Vincent, Augenlicht, Leonard, Klampfer, Lidija
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908545/
https://ncbi.nlm.nih.gov/pubmed/20661477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011700
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