Loading...

Study of the Efficacy, Biodistribution, and Safety Profile of Therapeutic Gutless Adenovirus Vectors as a Prelude to a Phase I Clinical Trial for Glioblastoma

Glioblastoma multiforme (GBM) is the most common and most aggressive primary brain tumor in humans. Systemic immunity against gene therapy vectors has been shown to hamper therapeutic efficacy; however, helper-dependent high-capacity adenovirus (HC-Ad) vectors elicit sustained transgene expression,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Muhammad, AKMG, Puntel, M, Candolfi, M, Salem, A, Yagiz, K, Farrokhi, C, Kroeger, KM, Xiong, W, Curtin, JF, Liu, C, Lawrence, K, Bondale, NS, Lerner, J, Baker, GJ, Foulad, D, Pechnick, RN, Palmer, D, Ng, P, Lowenstein, PR, Castro, MG
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908190/
https://ncbi.nlm.nih.gov/pubmed/20164833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2009.260
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!