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EAK-7 controls development and lifespan by regulating nuclear DAF-16/FoxO activity
FoxO transcription factors control development and longevity in diverse species. Although FoxO regulation via changes in its subcellular localization is well established, little is known about how FoxO activity is regulated in the nucleus. Here we show that the conserved C. elegans protein EAK-7 act...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907918/ https://ncbi.nlm.nih.gov/pubmed/20620993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.004 |
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