Загрузка...

Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation

The AGC family serine–threonine kinases Akt and Sgk are similar in primary amino acid sequence and in vitro substrate specificity, and both kinases are thought to directly phosphorylate and inhibit FoxO transcription factors. In the nematode Caenorhabditis elegans, it is well established that AKT-1...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Chen, Albert Tzong-Yang, Guo, Chunfang, Dumas, Kathleen J, Ashrafi, Kaveh, Hu, Patrick J
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824081/
https://ncbi.nlm.nih.gov/pubmed/23786484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12120
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!