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Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

Muscarinic acetylcholine receptors (mAChRs) have long been viewed as viable targets for novel therapeutic agents for the treatment of Alzheimer’s disease (AD) and other disorders involving impaired cognitive function. More recent evidence indicates that mAChR activators might also have utility in tr...

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Autori principali: Conn, P. Jeffrey, Jones, Carrie K., Lindsley, Craig W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907736/
https://ncbi.nlm.nih.gov/pubmed/19201489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.12.002
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