Llwytho...

Autophagy: PolyQ toxic fragment turnover

Recent studies have highlighted the importance of the lysosome in degrading proteins that misfold in neurodegenerative diseases. In this study we explore the role for autophagy in the clearance of an N-terminal caspase-7-generated fragment of ataxin-7, a protein with a pathogenic polyglutamine (poly...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duncan, Carlotta, Papanikolaou, Theodora, Ellerby, Lisa M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907151/
https://ncbi.nlm.nih.gov/pubmed/20104018
Tagiau: Ychwanegu Tag
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