8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC

The 8q24 gene desert contains risk loci for multiple epithelial cancers, including colon, breast, and prostate. Recent evidence suggests these risk loci contain enhancers. In this study, data are presented showing that each risk locus bears epigenetic marks consistent with enhancer elements and form...

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Detalhes bibliográficos
Main Authors: Ahmadiyeh, Nasim, Pomerantz, Mark M., Grisanzio, Chiara, Herman, Paula, Jia, Li, Almendro, Vanessa, He, Housheng Hansen, Brown, Myles, Liu, X. Shirley, Davis, Matt, Caswell, Jennifer L., Beckwith, Christine A., Hills, Adam, MacConaill, Laura, Coetzee, Gerhard A., Regan, Meredith M., Freedman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906844/
https://ncbi.nlm.nih.gov/pubmed/20453196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910668107
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