8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC

The 8q24 gene desert contains risk loci for multiple epithelial cancers, including colon, breast, and prostate. Recent evidence suggests these risk loci contain enhancers. In this study, data are presented showing that each risk locus bears epigenetic marks consistent with enhancer elements and form...

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Autori principali: Ahmadiyeh, Nasim, Pomerantz, Mark M., Grisanzio, Chiara, Herman, Paula, Jia, Li, Almendro, Vanessa, He, Housheng Hansen, Brown, Myles, Liu, X. Shirley, Davis, Matt, Caswell, Jennifer L., Beckwith, Christine A., Hills, Adam, MacConaill, Laura, Coetzee, Gerhard A., Regan, Meredith M., Freedman, Matthew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906844/
https://ncbi.nlm.nih.gov/pubmed/20453196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910668107
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