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Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

Fibroblast growth factor 21 (FGF21) has been identified as a potent metabolic regulator. Administration of recombinant FGF21 protein to rodents and rhesus monkeys with diet-induced or genetic obesity and diabetes exerts strong antihyperglycemic and triglyceride-lowering effects and reduction of body...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chau, Mary D. L., Gao, Jiaping, Yang, Qing, Wu, Zhidan, Gromada, Jesper
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906565/
https://ncbi.nlm.nih.gov/pubmed/20616029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006962107
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