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Predicting changes in protein thermostability brought about by single- or multi-site mutations
BACKGROUND: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostability is reflected in the change in free energy (ΔΔG) of thermal denaturation. RESULTS: We have developed predictive software...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906492/ https://ncbi.nlm.nih.gov/pubmed/20598148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-370 |
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